Expression profiles for oligonucleotides are shown as a function of location for chromosome II(A, Oligo Map). With the exception of the SERA locus (B), coregulated clusters of adjacent ORFs are seldom observed, indicating that expression phase is largely independent of chromosomal position. In contrast to the nuclear chromosomes, the polycistronic expression of the circular plastid genome is reflected in the tight coregulation of gene expression shown in (C). Genomic differences between strain 3D7, from which the complete genome was sequenced, and strain HB3, were measured by comparative genomic hybridization (CGH). The relative hybridization between the genomic DNA derived from these two strains is shown as a percent reduction of the signal intensity for 3D7 (A, CGH Data). Differences between the two strains are predominately located in the subtelomeric regions which contain the highly polymorphic var, rifin, and stevor gene families. Intrachromosomal variations, as observed for the MSP2 gene, were rare.
Download the data used to determine coregulation of genes compressed into a zip: Coregulation of genes (XXX KB)
Download all the Comparative genomic hybridization data compressed into a zip file: CGH data (45 MB)
Download the dataset for the apicoplast phaseogram, contained with all functional group datasets: Functional groups (219 KB)