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Figure 1. IDC Transcriptomes for three Plasmodium falciparum strains. The phaseograms depict the 48-hour progression of gene expression throughout the IDC from the early ring stage to merozoite invasion (left to right) for the 3D7, Dd2 and HB3 strains of P. falciparum. The profiles have been ordered (top to bottom) by the phase of gene expression during the IDC and demonstrate a highly similar cascade across the three strains. Depicted above the phaseograms (in grayscale) is the relative percentage of the three morphological stages -- ring, trophozoite (troph), and schizont. |