All of the GPR files for 3D7 and Dd2 are missing the normal Headers from a GenePix .gpr file. This means that the first 29 lines of a normal GPR file are absent. These usually look something like this: ATF 1 27 43 Type=GenePix Results 1.4 DateTime=2004/01/21 13:03:52 Settings=C:\Filelocation\file.gps GalFile=C:\Filelocation\file.gal.txt Scanner=GenePix 4000B [88593] Comment= PixelSize=10 "ImageName=635 532" "FileName=C:\Filelocation\file_635.tif C:\Filelocation\file_532.tif" "PMTVolts=610 530" "ScanPower=100 100" FocusPosition=0 NormalizationFactor:RatioOfMedians=1.19836 NormalizationFactor:RatioOfMeans=1.20461 NormalizationFactor:MedianOfRatios=1.22357 NormalizationFactor:MeanOfRatios=1.21427 NormalizationFactor:RegressionRatio=1.22495 JpegImage=C:\Filelocation\file.jpg RatioFormulation=W1/W2 (635/532) Barcode= ImageOrigin=980, 19870 JpegOrigin=980, 19870 Creator=GenePix Pro 3.0.6.73 Temperature=32.34 "LaserPower=3.4 3.62" "LaserOnTime=50408 50454" Supplier= Therefore, to open up in GenePix you will need to add these lines, otherwise not.